Asked by: Seydou Salisasked in category: General Last Updated: 17th June, 2020
What is factor 2a?
Simply so, what is factor IIa?
A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting; used as a topical hemostatic for capillary bleeding in general and plastic surgical procedures. Synonym(s): factor IIa.
One may also ask, what activates prothrombin to thrombin? Prothrombin is transformed into thrombin by a clotting factor known as factor X or prothrombinase; thrombin then acts to transform fibrinogen, also present in plasma, into fibrin, which, in combination with platelets from the blood, forms a clot (a process called coagulation).
One may also ask, what is the function of thrombin?
Thrombin is an unique molecule that functions both as a procoagulant and anticoagulant. In its procoagulant role it activates platelets through its receptor on the platelets. It regulates its own generation by activating coagulation factors V, VIII and even XI resulting in a burst of thrombin formation.
Is Thrombin a factor of 10?
Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Prothrombin is produced in the liver and is co-translationally modified in a vitamin K-dependent reaction that converts 10-12 glutamic acids in the N terminus of the molecule to gamma-carboxyglutamic acid (Gla).